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Outcome measures cover histological damage scoring, cytokine panels (TNF-, IL-6, IL-10), mucosal blood flow, tight junction protein expression by Western blot, and stool consistency scoring for colitis models

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Week 78: Add 5-Amino-1MQ (5mg/day to start, increase to 1025mg/day based on tolerance) Running simultaneously (established protocol): If you're already on GLP-1 therapy and want to add the full stack, all four can be added simultaneously